Neurodegenerative diseases are characterized by gradually progressive, selective loss of anatomically or physiologically related neuronal systems that produce brain damage from which there is no recovery.Despite the differences in clinical manifestations and neuronal vulnerability, the pathological processes appear to be similar, suggesting common
Site-2 proteases (S2P) belong to the M50 family of metalloproteases, which typically perform essential roles by mediating activation of membrane-bound transcription factors through regulated intramembrane proteolysis (RIP).Protease-dependent liberation of dormant transcription factors triggers diverse cellular responses, such as sterol regulation,
West Nile virus (WNV) berness white sneakers is a member of the Flaviviridae family of vector-borne pathogens.Clinical signs of WNV infection include neurologic symptoms, limb weakness, and encephalitis, which can result in paralysis or death.We report that the WNV-capsid (Cp) by itself induces rapid nuclear condensation and cell death in tissue cu
In this work, the utilization of waste paper in the preparation of cellulous-based composite is described, with latex as a binder.Paraffin wax and acrylic woven fibers were also used at various weight ratios to get the best mechanical and physical properties.The results were compared with the performance the Dixon, regularly used material in shoes
A pure 27 graph (G) of order (n) is said to be arbitrarily vertex decomposable if for each sequence ((n_{1},ldots,n_k)) of positive integers such that (n_{1}+ldots+n_{k}=n) there exists a partition ((V_{1},ldots,V_{k})) of the vertex set of (G) such that for each (i in {1,ldots,k}), (V_{i}) induces a connected subgraph of (G) on (n_i) vertices.In t